Gandhi Medicos
Gurgaon, Haryana
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Hepatitis C Medicine

Leading Wholesaler of ledipasvir with sofosbuvir tablets, eltrombopag tablets, sofosbuvir tablets 400mg, sovihep v tablets, sofosbuvir tablets and ledipasvir and sofosbuvir tablets from Gurgaon.
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Ledipasvir With Sofosbuvir Tablets
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Ledipasvir With Sofosbuvir Tablets

Approx. Price: Rs 5,000 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
CompositionLedipasvir With Sofosbuvir
Prescription/Non prescriptionPrescription
BrandLedihep
ManufacturerZydus Heptiza
FormTablet
Other Details:

  • Ledihep is a prescription drug and should be used under proper medical guidance and advice
  • The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers

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Eltrombopag Tablets
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Eltrombopag Tablets

Approx. Price: Rs 15,194 / BoxGet Latest Price
Product Details:
Packaging Size2 x 7 Tablets
BrandRevolade
CompositionEltrombopag
ManufacturerNovartis
Prescription/Non prescriptionPrescription
FormTablet
Strength50 mg
Uses Revolade 50 mg tablet is used in the treatment of chronic idiopathic thrombocytopenia How it works Revolade 50 mg tablet belongs to class of drugs called antihemorrhagics. It works by activating the production and proliferation of platelets from bone marrow.Common side effects Nausea, Running nose, Back pain, Rash, Muscle pain, Mouth ulcer, Musculoskeletal pain, Oropharyngeal pain, Fever, Upper respiratory tract infection, Nasopharyngitis, Paresthesia (tingling or pricking sensation), Hair loss, Dry eye, Cough, Toothache, Increased liver enzymes, Menorrhagia (heavy menstrual bleeding), Bone pain, Diarrhoea, Muscle cramp

1 strip(s) (7 tablets

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Sofosbuvir Tablets 400mg
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Sofosbuvir Tablets 400mg

Approx. Price: Rs 3,500 / BoxGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400mg
BrandSpegra
ManufacturerEmcure
FormTablet
Packaging TypeBox

Spegra Tablets is a prescription drug and should be used under proper medical guidance and advice.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

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Sofosbuvir Tablets 400mg
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Sofosbuvir Tablets 400mg

Approx. Price: Rs 3,500 / BoxGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400mg
BrandHepcinat
ManufacturerNatco
FormTablet
To meet the diverse demands of our precious clients, we are engaged in exporting, retailing and wholesaling an optimum quality Hepcinat Tablet. The offered tablet is used to cure people of the Hep C virus along with combination of other medications. To process this tablet, our vendors’ professionals use only high grade chemical compounds and the latest technology in sync with predefined industry quality norms. Apart from this, offered tablet is available in different packaging options as per the needs of our clients.

Features:


  • Accurate composition
  • Hygienically packed
  • Effectiveness


Other Details: 28 Tablets.



Additional Information:

  • Item Code: 400mg

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SoviHep V Tablets
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SoviHep V Tablets

Approx. Price: Rs 9,000 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength500mg
CompositionSofosbuvir 400mg and Velpatasvir 100mg
BrandSoviHep V
ManufacturerZydus Heptiza
FormTablet
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Sofosbuvir Tablets
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Sofosbuvir Tablets

Approx. Price: Rs 4,000 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400 mg
BrandSofovir
ManufacturerHetero
FormTablet
We are extremely engaged in offering an incomparable quality Sofovir Tablet. Directly targets the hepatitis c virus to stop it from making copies of itself in the liver and makes it harder for the virus to multiply, offered tablet is processed under guidance of vendor professionals using the best quality chemical compounds and cutting edge technology. So as to offer a qualitative product, this tablet is rigorously tested on different parameters of quality. Apart from this, we provide this tablet in various packaging options so as to maintain its quality. 

Features:


  • Temper proof packing
  • No side effects
  • Safe packaging


Other Details: 7 Tablets.


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Ledipasvir and Sofosbuvir Tablets
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Ledipasvir and Sofosbuvir Tablets

Approx. Price: Rs 5,500 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
BrandLedikast
ManufacturerAprazer
FormTablet
Packaging TypeBottles

Brand Name LEDIKAST
Contents Ledipasvir and Sofosbuvir
Marketed by Aprazer Health Care
Manufactured by Natco Pharma Limited
Strength - Each film-coated tablet Contains 90 mg Ledipasvir and 400 mg Sofosbuvir
Form Tablets
Packing Pack of 28 Tablet

Each film-coated tablet contains 90 mg ledipasvir and 400 mg sofosbuvir. The tablet includes the following inactive ingredients colloidal silicon dioxide, copovidone, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose. The tablet is film-coated with a coating material containing the following inactive ingredients Yellow Oxide of Iron, polyethylene glycol, polyvinyl alcohol, talc, FD&C Blue #2 and titanium dioxide IP. -

Ledipasvir The IUPAC name for ledipasvir is Methyl [(2S)-1-{(6S)-6-[5-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2azabicyclo[2.2.1] hept-3-yl]-1H-benzimidazol-6-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4] hept-5-yl}-3-methyl-

 


2.1 Mechanism of Action

Ledikast is a fixed-dose combination of ledipasvir and sofosbuvir which are directacting antiviral agents against the hepatitis C virus.

2.2 Pharmacodynamics

Cardiac Electrophysiology

Ledipasvir at a dose of 120 mg twice daily (2.67 times the maximum recommended dosage) and sofosbuvir 400 mg (maximum recommended dosage) and 1200 mg (three times the maximum recommended dosage) does not prolong QTc in clinical trials -


2.3 Pharmacokinetics

Absorption

The pharmacokinetic properties of ledipasvir, sofosbuvir, and the predominant circulating metabolite GS-331007 have been evaluated in healthy adult subjects and in subjects with chronic hepatitis C. Following oral administration, ledipasvir median peak concentrations were observed 4 to 4.5 hours post-dose. Sofosbuvir was absorbed quickly and the peak median plasma concentration was observed ~0.8 to 1 hour post dose. Median peak plasma concentration of GS-331007 was observed between 3.5 to 4 hours post-dose.

Based on the population pharmacokinetic analysis in HCV-infected subjects, geometric mean steady-state AUC0-24 for ledipasvir (N=2113), sofosbuvir (N=1542), and GS-331007 (N=2113) were 7290, 1320, and 12,000 ng-hr/mL. Steady-state Cmax for ledipasvir, sofosbuvir, and GS-331007 were 323, 618, and 707 ng/mL. Sofosbuvir and GS-331007 AUC0-24 and Cmax were similar in healthy adult subjects and subjects with HCV infection. Relative to healthy subjects (N=191)



Ledipasvir is >99.8% bound to human plasma proteins. After a single 90 mg dose of [14C]-ledipasvir in healthy subjects, the blood to plasma ratio of [14C]-radioactivity ranged between 0.51


Sofosbuvir is approximately 61-65% bound to human plasma proteins and the binding is independent of drug concentration over the range of 1 g/mL to 20 g/mL. Protein binding of GS-331007 was minimal in human plasma. After a single 400 mg dose of [14C]-sofosbuvir in healthy subjects, the blood to plasma ratio of 14C-radioactivity was approximately 0.7.


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Velpanat 100mg Tablets
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Velpanat 100mg Tablets

Approx. Price: Rs 11,500 / PacketGet Latest Price
Product Details:
BrandVelpanat
Manufactured ByNatco
CompositionSofosbuvir 400mg and Velpatasvir 100mg
Packaging Size28 Tablets
FormTablet
Velpanat 400mg/100mg Tablet is used in combination with other medications such as ribavirin, daclatasvir and peginterferon to treat chronic hepatitis C. It functions by reducing the hepatitis C virus in the body. This helps to keep liver disorders such as cirrhosis and liver cancer at bay.

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Ribavirin Capsules USP 200mg
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Ribavirin Capsules USP 200mg

Approx. Price: Rs 1,200 / BottleGet Latest Price
Product Details:
FormCapsule
Brand NameRibasure
Packaging TypeBox
Strength200 mg
Manufactured ByAprazer
Ribasure Capsule is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

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HepBest Tablets 25mg
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HepBest Tablets 25mg

Approx. Price: Rs 1,488 / BoxGet Latest Price
Product Details:
BrandHepBest
Manufactured ByMylan
Strength25mg
Packaging Size30 Tablets
FormTablet
CompositionTenofovir Alafenamide
Up to 20% Discount

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Velasof Tablets
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Velasof Tablets

Approx. Price: Rs 10,000 / BottleGet Latest Price
Product Details:
CompositionSofosbuvir 400mg and Velpatasvir 100mg
BrandVelasof
FormTablet
Packaging Size28 Tablets
Packaging TypeBottle

Velpatasvir Sofosbuvir ( Tab Velasof ) by Hetero is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It is also used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.

Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

Sofosbuvir 400 mg Velpatasvir 100 mg Indication :

Velasof ( Sofosbuvir 400 mg velpatasvir 100 mg) is used alone or with ribavirin to treat chronic hepatitis C. Sofosbuvir is in a class of antiviral medications called nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Velpatasvir is in a class of antiviral medications called HCV NS5A replication complex inhibitors.

The combination of sofosbuvir and velpatasvir works by stopping the virus that causes hepatitis C from spreading inside the body.


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Entecavir Tablets
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Entecavir Tablets

Approx. Price: Rs 1,200 / BoxGet Latest Price
Product Details:
Packaging Size30 Tablets
Strength0.5 mg
BrandX-VIR
ManufacturerNatco
FormTablet
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Sofosbuvir Tablets 400mg
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Sofosbuvir Tablets 400mg

Approx. Price: Rs 4,200 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400 mg
BrandSofokast
ManufacturerAprazer
FormTablet
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Hepcvir Sofosbuvir Tablets 400 Mg
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Hepcvir Sofosbuvir Tablets 400 Mg

Approx. Price: Rs 2,800 / BottleGet Latest Price
Product Details:
Packaging Size15 Tablets
Strength400mg
BrandHepcvir
ManufacturerCipla Ltd
FormTablet
Hepcvir Sofosbuvir Tablets 400 mg

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Sofosbuvir Tablets 400 mg
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Sofosbuvir Tablets 400 mg

Approx. Price: Rs 3,200 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400mg
BrandSofocure
ManufacturerEmcure
FormTablet
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Entecavir Tablets IP 0.5 mg
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Entecavir Tablets IP 0.5 mg

Approx. Price: Rs 2,459.52 / BottleGet Latest Price
Product Details:
Packaging Size30 Tablets
Strength0.5 mg
BrandEntaliv
ManufacturerDr. Reddy's
FormTablet
Up To 45 % Discount

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Ledipasvir 90mg and Sofosbuvir 400mg Tablets
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Ledipasvir 90mg and Sofosbuvir 400mg Tablets

Approx. Price: Rs 6,000 / BottleGet Latest Price
Product Details:
Packaging Size1x28 Tablets
Strength490 mg
CompositionLedipasvir 90mg and Sofosbuvir 400mg
BrandLedviclear
FormTablet
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Resof Sofosbuvir Tablets 400 Mg
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Resof Sofosbuvir Tablets 400 Mg

Approx. Price: Rs 4,000 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength400mg
BrandResof
ManufacturerDr. Reddy's
FormTablet
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Natdac Daclatasvir Dihydrochloride Tablets 60 Mg
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Natdac Daclatasvir Dihydrochloride Tablets 60 Mg

Approx. Price: Rs 1,400 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60mg
BrandNatdac
ManufacturerNatco
FormTablet
Prescription/Non prescriptionPrescription
Packaging TypeBottles

With our in-depth knowledge and rich industry experience in this field, we are highly engaged in exporting, retailing, wholesaling and supplying a qualitative NATDAC Tablet for our esteemed clients. Processed employing advanced technology and using premium quality chemical compounds, offered tablet should only be used under proper medical guidance and advice. In order to maintain the effectiveness, our quality examiners test this tablet on various parameters. 

Features:

  • Highly effective
  • Long shelf life
  • Balanced composition

 

Other Details: 28 Tablets.


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Hepcdac Tablets
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Hepcdac Tablets

Approx. Price: Rs 1,500 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60 mg
CompositionDaclatasvir
Prescription/Non prescriptionPrescription
BrandHepcdac
ManufacturerCipla Ltd
FormTablet
Hepcdac Tablet is an antiviral medication used for the treatment of chronic hepatitis C in adults. It is normally used in a combination with sofosbuvir, with or without ribavirin. However, this medicine is not recommended for use as a preventive option for the spread of hepatitis C.

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Daclatasvir Tablets 60 mg
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Daclatasvir Tablets 60 mg

Approx. Price: Rs 1,800 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60mg
BrandDaclahep
ManufacturerHetero
FormTablet
We are extremely engrossed in exporting, retailing, wholesaling and supplying a premium quality Daclahep Tablet. The offered tablet is processed utilizing superior quality chemical compounds and the latest technology in compliance with industry norms. The offered tablet when used in combination with sofosbuvir may result in slowing of the heart rate. Apart from this, we offer this tablet in various packaging options so as to maintain its long shelf life.

Features:


  • 100% safe
  • Safe to consume
  • Free from impurities


Other Details: 28 Tablet


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Hepcfix Tablets 60mg
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Hepcfix Tablets 60mg

Approx. Price: Rs 1,500 / BoxGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60mg
BrandHepcfix
ManufacturerDr. Reddy's
FormTablet
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Daclatasvir Dihydrochloride Tablets
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Daclatasvir Dihydrochloride Tablets

Approx. Price: Rs 1,500 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60 mg
CompositionDaclatasvir Dihydrochloride
Prescription/Non prescriptionPrescription
BrandDaclacure
ManufacturerEmcure
FormTablet
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Sofosbuvir and Velpatasvir Tablets
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Sofosbuvir and Velpatasvir Tablets

Approx. Price: Rs 9,000 / BoxGet Latest Price
Product Details:
CompositionSofosbuvir 400mg and Velpatasvir 100mg
BrandVelakast
Manufactured ByAprazer
Packaging Size28 Tablets
FormTablet
VELAKAST is a fixed-dose combination tablet containing sofosbuvir and velpatasvir for oral administration. Sofosbuvir is a nucleotide analog HCV NS5B polymerase inhibitor and velpatasvir is an NS5A inhibitor. Each tablet contains 400 mg sofosbuvir and 100 mg velpatasvir. The tablets include the following inactive ingredients: copovidone, croscarmellose sodium, magnesium stearate, and microcrystalline cellulose. The tablets are film-coated with a coating material containing the following inactive ingredients: Titanium Dioxide IP and Brilliant Blue FCF, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.
Effect of the drug
Thanks to the powerful composition of the drug, Velakast APRAZER HEALTHCARE is widely used to fight the hepatitis C virus of genotypes 1-6. The drug may be given as a monotherapy or for combined treatment with or without cirrhosis. The high effectiveness of the drug against all genotypes of HCV is due to the presence in its composition:
Sofosbuvir: The IUPAC name for sofosbuvir is (S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5(2,4-dioxo-3,4-dihydropyrimidin- 1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran- 2yl)methoxy  (phenoxy)phosphorylamino)propanoate. It has a molecular formula of C22H29FN3 O9 P and a molecular weight of 529.45. Sofosbuvir is a white to off-white crystalline solid with a solubility of at least 2 mg/mL across the pH range of 2–7.7 at 37°C and is slightly soluble in water.
Velpatasvir: The IUPAC name for velpatasvir is Methyl {(1R)-2-[(2S,4S)-2-(5-{2[(2S,5S)-1-{(2S)-2-[(methoxycarbonyl) amino]-3-methylbutanoyl}-5-methylpyrrolidin-2-yl]1,11-dihydro[2]benzopyrano[4′,3′:6,7]naphtho[1,2-d]imidazol-9- yl}-1H-imidazol-2-yl)-4(methoxymethyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate. It has a molecular formula of C49H54 N8 O8 and a molecular weight of 883.0. Velpatasvir is practically insoluble (less than 0.1 mg/mL) above pH 5, slightly soluble (3.6 mg/mL) at pH 2, and soluble (greater than 36 mg/mL) at pH 1.2.
Mechanism of Action
VELAKAST is a fixed-dose combination of sofosbuvir and velpatasvir which are direct-acting antiviral agents against the hepatitis C virus Sofosbuvir is an inhibitor of the HCV NS5B RNA-dependent RNA polymerase, which is required for viral replication. Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form the pharmacologically active uridine analog triphosphate (GS-461203), which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator. In a biochemical assay, GS-461203 inhibited the polymerase activity of the recombinant NS5B from HCV genotype 1b, 2a, 3a and 4a with an IC50 value ranging from 0.36 to 3.3 micromolar. GS-461203 is neither an inhibitor of human DNA and RNA polymerases nor an inhibitor of mitochondrial RNA polymerase. Velpatasvir is an inhibitor of the HCV NS5A protein, which is required for viral replication. Resistance selection in cell culture and cross-resistance studies indicates velpatasvir targets NS5A as its mode of action.
OVERDOSAGE
No specific antidote is available for overdose with VELAKAST. If overdose occurs the patient must be monitored for evidence of toxicity. Treatment of overdose with VELAKAST consists of general supportive measures including monitoring of vital signs as well as observation of the clinical status of the patient. Hemodialysis can efficiently remove the predominant circulating metabolite of sofosbuvir, GS-331007, with an extraction ratio of 53%. Hemodialysis is unlikely to result in significant removal of velpatasvir since velpatasvir is highly bound to plasma protein.
HOW SUPPLIED AND STORAGE
Each bottle contains 28 tablets and is closed with a child-resistant closure. Storage: Store below 30°C

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Ledifos Tablets
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Ledifos Tablets

Approx. Price: Rs 6,500 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength490mg
CompositionLedipasvir 90mg and Sofosbuvir 400mg
BrandLedifos
ManufacturerHetero
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Daclatasvir Dihydrochloride Tablets 60mg
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Daclatasvir Dihydrochloride Tablets 60mg

Approx. Price: Rs 2,050 / BottleGet Latest Price
Product Details:
Packaging Size28 Tablets
Strength60mg
BrandDaciHep
ManufacturerZydus Heptiza
FormTablet
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Sofosbuvir Velpatasvir Tablets
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Sofosbuvir Velpatasvir Tablets

Approx. Price: Rs 9,000 / BottleGet Latest Price
Product Details:
CompositionSofosbuvir 400mg + Velpatasvir 100mg
Packaging Size28 Tablets
BrandHepcvel
Manufactured ByCipla
FormTablet
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Sofosbuvir 400mg Velpatasvir 100mg Tablets
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Sofosbuvir 400mg Velpatasvir 100mg Tablets

Approx. Price: Rs 8,500 / BottleGet Latest Price
Product Details:
CompositionSofosbuvir 400mg and Velpatasvir 100mg
Packaging Size1 x 28 Tablets
BrandVelpaclear
Strength500 mg
Manufactured ByAbbott
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Sofosbuvir 400mg and Velpatasvir 100mg Tablets
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Sofosbuvir 400mg and Velpatasvir 100mg Tablets

Approx. Price: Rs 11,000 / BottleGet Latest Price
Product Details:
BrandResof
Strength500mg
Manufactured ByDr. Reddy's
Packaging TypeBottle
CompositionSofosbuvir 400mg and Velpatasvir 100mg
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